Ten to fifteen percent of people are genetically slow acetylators of isoniazid (INH), the antibacterial most often used to treat tuberculosis. Cold therapy (ice packs on breasts for 15 minutes, 3-4 times per day). Disulfiram (sold under the trade name Antabuse) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Nursing interventions: Monitor serum levels for toxicity at levels >20 mcg/mL; Mild toxicity can cause GI distress and restlessness; Moderate to severe toxicity can cause dysrhythmias and seizures Theophylline (Theolair) is the prototype medication and is used for long-term control of chronic asthma. Asthma is a chronic respiratory disease that causes inflammation to the smaller airways. The symptoms of CNS toxicity, as mentioned earlier, usually come on much more abruptly and have the potential to do far more damage if the patient fails to take action quickly. The nurse should recognize that which of the following findings is a manifestation of levothyroxine overdose? a Insomnia i Rationale: Levothyroxine overdose will result in manifestations of hyperthyroidism which include Insomnia tachycardia and hyperthermia. The nurse instruct the client to increase the intake of which food items?A. If dialysis is done quickly, the person may feel much better. INH is an inhibitor of the 2C9 and 2C19 cytochrome P-450 isoenzyme systems, of which the antiepileptic drug phenytoin is a substrate. Severe reactions • Severe reactions can occur at therapeutic levels and include dysrhythmias and seizures. Milk.C. NURS PHARM ATI EXIT EXAM: THINGS TO REMEMBER What are some expected findings of theophylline toxicity? Treatment of Bordetella pertussis in a patient with a hypersensitivity to macrolides is: 2. 1. What do you do if your patient experiences bowel protrusion? For example, levels above 1.2 mmol/L can cause severe side effects, including nausea, vomiting, and tremors [ 13 ]. The physician asks the nurse to teach the client to consume thiamine-rich food. The most common adverse events with peak serum theophylline levels under 20 mcg/mL are transient caffeine-like events such as nausea, vomiting, headache, and insomnia. B. Theophylline level of 5 mcg/ml C. Theophylline level of 20mcg/ml D. Theophylline level of 25mcg/ml. Study Flashcards On Adult Health Test #1 Chapters 1-25 and ATI Drugs at Cram.com. Cromolyn belongs to a class of medications called mast cell stabilizers. Nursing interventions: Monitor serum levels for toxicity at levels >20 mcg/mL; Mild toxicity can cause GI distress and restlessness; Moderate to severe toxicity can cause dysrhythmias and seizures Study 53 ATI-Respiratory Pharmacology flashcards from ZAK K. on StudyBlue. Patients and family members should be warned of the signs and symptoms of impending lithium toxicity such as: gastrointestinal: progressive anorexia, diarrhoea and vomiting. ATI NR293 Pharm Final Review 1 A nurse is assessing a client who is taking levothyroxine. Corticosteroids act, at least in part, by recruitment of histone deacetylases (HDACs) to the site of active inflammatory gene transcription. Other symptoms that may be present are nausea, vomiting and flushing of the skin. Cardiovascular and neurological side-effects are more serious. AGNP BOARD EXAM QUESTIONS Respiratory Prescribing Questions 100 1. Acute on chronic overdose often has a poor outlook. A blood level between 5-15 µg/ml often gives good relief of symptoms with the fewest side effects. Benzodiazepines ↑toxicity Anti-epileptics ↑toxicity of carbamazepine and phenytoin Disulfiram (Antabuse) Psychotic episodes Haloperidol ↑toxicity antipsychotics Ketoconazole ↓efficacy of ketoconazole Dilantin ↑toxicity antiepileptic Theophylline ↑toxicity theophylline; monitor levels Valproate ↑hepatic and CNS toxicity The most common side-effects are gastrointestinal, such as nausea and vomiting. Anorexia, Tachycardia, Albuminuria, and Hypotension How is breast engorgement treated? This is due to the blocking of the transmission in the neuromuscular receptors. Digoxin NCLEX questions for nursing students! Chicken.B. Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, causing many of the effects of a hangover to be felt immediately following alcohol consumption. The main problems with theophylline use are toxicity and potential interactions. concurrent use of theophylline (Theo-Dur) can lead to theophylline toxicity Zidophine (Retrovir) may increase the risk of neutropenia or thrombocytopenia concurrent use with meds that are cardiotoxic or netrotoxic may increase cardiotoxicity or neurotoxicity Propylthiouracil (PTU) is an oral medication that is used to manage hyperthyroidism which is due to an overactive thyroid gland. Alprazolam: (Moderate) Aminophylline has been reported to … 3. Study ATI section 4: respiratory meds flashcards from Kandace Swagerty's class online, ... -Warfarin and theophylline toxicity ... -children may have symptoms of excitation, hallucinations, incoordination, and seizures-Avoid alcohol intake Symptoms. The blood pressure will also decrease at this point. Monitor theophylline concentrations and for signs and symptoms of theophylline toxicity when interferons are used concomitantly; consider appropriate dose adjustments as clinically indicated. Effects unlikely @ <20 mcg/mL. The molecular mechanism for the anti-inflammatory action of theophylline is currently unknown, but low-dose theophylline is an effective add-on therapy to corticosteroids in controlling asthma. Chronic toxicity is sometimes hard to diagnose at first. The nurse should be aware of how the drug works, why it is ordered, nursing implications, signs and symptoms of toxicity, and how to teach the patient how to take the medication. If these people are given the two drugs concurrently, phenytoin will significantly accumulate.79 INH Beef.D. This is a quiz that contains NCLEX review questions for asthma. It is an anti-thyroid drug that has a mechanism of action that is similar to methimazole (). In the previous NCLEX review series, I explained about other respiratory disorders, so be sure to check those reviews out. Answer: A theophylline level is a measure of theophylline in the bloodstream. But symptoms such as memory and mood problems may be permanent. Digoxin is a medication used to help the heart pump more efficiently, and it is used for many cardiac conditions. Welcome to your ultimate set of nursing pharmacology questions for the NCLEX!In this nursing test bank, test your competence in nursing pharmacology with these 500+ practice NCLEX questions.The goal of this quiz is to help nursing students review concepts of nursing pharmacology and provide an alternative to Quizlet or ATI. Option D: Theophylline toxicity is likely to occur when the serum level is higher than 20 mcg/ml. Early signs of toxicity include restlessness, nervousness, tachycardia, tremors, and palpitations. A nurse is caring for a client with Wernicke-Korsakoff syndrome. Answer: D. Theophylline level of 25mcg/ml. Specific symptoms include changes in vision and hearing, anxiety, irritability, mental confusion, nausea, vomiting, dizziness, loss of consciousness and convulsions. This delay can lead to long-term problems. 4. When serum theophylline exceeds 20 mcg/mL a wide range of adverse events may occur, including persistent vomiting, cardiac arrhythmias, and potentially lethal intractable seizures. Theophylline (Theolair) is the prototype medication and is used for long-term control of chronic asthma. This can lead to symptoms such as diarrhea, stomach/abdominal pain, itching, rash, and flushing. One of the initial magnesium sulfate toxicity symptoms is a decrease in the reflexes of the person. Very high levels (above 2.0 mmol/L) can cause permanent brain damage and even lead to death [ 13 ]. This is used to regulate the dose. Cram.com makes it easy to get the grade you want! Quickly memorize the terms, phrases and much more. Expected Action: Proto: Theophylline (Theolair) • Theophylline relaxes bronchial smooth muscle bronchodilation Therapeutic Uses: • Long-term control of asthma Adverse Effects: • Mild toxicity GI distress & restlessness. Theophylline can produce cardiac arrhythmias and, when given in overdose, has been associated with sudden death. This is used to regulate the dose. High levels of lithium in the blood can cause side effects and lead to toxicity . Brocolli., The nurse is teaching a client who has iron deficiency anemia about foods she should include in her diet. The mainstay of treatment in the management of mild and moderate croup is symptomatic relief that includes: 3. Aminophylline has been reported to … the main problems with theophylline theophylline toxicity symptoms ati are toxicity and potential interactions felt following! 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